My best bench was a 245 max in college, with a bodyweight of 175. Now, I'm closer to 180 and am doing reps at 145-150. I have a tender shoulder, so I've cut the barbell bench and have gone to dumbell bench with 45-50 lb weights. Anything more, and I'm sore in my right shoulder.
I agree 100% that lifting properly is very safe for most people, and actually can help to prevent injury. It's when you try and lift too heavy or too often than you can injure yourself.