I too have have been seduced by the siren song of more spin and power from larger heads/open string beds. But repeatedly I find myself leaving those 100" mistresses and returning to my control freaks with their smaller heads/dense patterns.
If you insist on heading down this road towards maddness then there are few options. Depeneding upon the frame's power you'll need to do what the pros do: string with full bed poly or something like gut at a very high tension. Anything else and coming from a smaller head you'll be disappointed with the lower control. Even then I predict you'll return to smaller heads once you realize larger ones don't provide a significant increase in spin or sweet spot.
Only on Talk Tennis can you find people who believe
that 10 feet of lead tape has no effect on a frame...