Bigger head means bigger sweetspot for sure.
What Timothy says is that a 100hs racket has less directional control than a 95. So to overcome this, if you buy an 100 you should string it very high.
An 95 racket has already enough control potential, so smaller rackets could be strung with less tension in order to get some power.
But i have maybe the same problem with you.
I use a BLX 6.1 95 16x19 2011. I like everything about this racket (weight, swingweight, maneuverability, control, power), but i have some annoying off-spot hits.
Any proposals on a 100hs with similar specs as the 6.1?
The new Head Extreme Pro 2.0 seems good, but i'm afraid that would be very generic...