Gut, even as a cross string, is going to offer a different feel and response to a multi. If you can feel the difference, and like it, then gut is worth the investment. If you can't or don't, then go with a multi and save! Tecnifibre E-Matrix is a great budget option as a cross with a poly.
Expect the Pacific to feel a little crisper. VS feels more dampened to me (until the coating wears off).
I would drop 2-3lbs with the addition of gut as a cross.
I have never tried N.Vy as a cross string, but you are getting away from multis and even further from gut with its solid core.