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Old 01-19-2013, 07:57 PM   #13
Raul_SJ's Avatar
Join Date: May 2011
Location: San Jose, California
Posts: 1,201

I have been reading the links below and it seems the studies are ongoing, unless I am missing some recent news...

Meniscal Tear With Osteoarthritis Research (MeTeOR) study

Comparing arthroscopy to nonoperative therapy for meniscal tears in patients with osteoarthritis of the knee

Each year in the United States, more than 300,000 knee arthroscopies are performed for patients who have both a meniscal tear and osteoarthritis in the same compartment of the knee. Yet the frequency with which this treatment is performed belies significant uncertainty surrounding outcomes associated with its use.

Ambiguity and arthroscopy

Mayo orthopedic surgeon Bruce A. Levy, MD, explains that the challenge starts in the consult room, when a patient presents with, for example, medial-sided knee pain. "But if they have a medial meniscus tear and concomitant medial compartment osteoarthritis, it is almost impossible to figure out what is generating the pain," Dr Levy says. "Is it the meniscal tear? Or is it the osteoarthritis in the medial compartment?"

This ambiguity over the identity of pain origin and generation is problematic because meniscal tears and osteoarthritis tend to respond differently to arthroscopy. Data show that arthroscopy is very effective in treating meniscal tears without osteoarthritis and highly ineffective for treating advanced osteoarthritis of the knee.

MeTeOR to clarify treatment

But what is the best course of treatment when both conditions are present? Currently physicians tell this subset of patients who are contemplating treatment that knee arthroscopy is unpredictable in the setting of meniscal tear and concomitant osteoarthritis.

MeTeOR at a glance

Enrollment goal: 340 by February 2011
Mayo Clinic contribution to total enrollment: ~80 patients

Centers involved: 7 U.S. advanced orthopedic centers, sponsored by the National Institutes of Health
Principal Investigator: Jeffrey N. Katz, MD, MS, Brigham and Women's Hospital, Boston
Mayo Clinic investigators: Bruce A. Levy, MD, Diane L. Dahm, MD, Michael J. Stuart, MD

Randomized to 2 arms: Arthroscopy vs nonoperative treatments. These treatments may include physical therapy, use of antiinflammatory drugs, intraarticular cortisone injections, activity modification, braces.
Main inclusion criteria > age 45:

Presence of symptomatic meniscal tear with mechanical indicators such as locking, buckling, catching
Presence of mild to moderate osteoarthritis on MRI
No comorbidities, not pregnant
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