I'm a runner as well. Anywhere from 2-7 miles per run depending on what's happening that week. I rotate between Brooks Glycerin 9's, Nike Zoom Vomero 6's, and Brooks Ghost 4's.
I've tried a number of high end tennis shoes with all the bells and whistles. Most of the popular shoes have some sort of plastic support piece in the midsole, and for the most part, all that stuff did was inhibit my movement forward, and some caused some degree of foot, or arch discomfort at some point.
I'm playing in the K-Swiss Ultrascendor II's right now, and they're the best shoes I've ever played with. They're light, stable, and the cushioning is just as good as the more expensive and popular shoes I've tried. I'm hoping K-Swiss keep them in production, and they do like the original Ultrascendor, and not change anything about it.