If you already have a Used Neos 1000 why not just add a Wise, if space is not problem. If you spent $1K+ on an USED NEOS, that's almost the price of a brand new one. I know of a couple of places that are selling used Neos 1000 for $895.
You can probably get a USED Gamma 4000, if you like glide bars; and put a Wise on it with not too much problems. It's been done and there are many threads on putting a Wise on a DW machine.
If you mean "effective" to work, the answer is "YES".
Machines: Gamma 6004 2-point w/ Wise 2086 & Babolat Sensor Dual