The APDC used to be my main stick. No TE issue whatsoever with poly/gut hybrid, no problem at all with full bed of multi. Had a little bit of elbow pain (but most likely due to hyper extension) with a poly/Nvy hybrid.
When in doubt, use gut hybrid and string @52-48. If cost is an issue use a full bed of multi but beware of drop tension or breakage.
The other end of the equation is your grip pressure and swing. I know for a fact if you don't forearm or use a straight arm fh you will be fine. 2hbh is also 100x better for your TE than 1hbh.