I've tried several Gut/Multi hybrids hoping to find something longer lasting and more comfortable than Gut/Poly.
Nothing I tried compares to Gut/Poly's unique combination of control and spin. Every Gut/Multi I tried provided less control and less "casually accessible" spin potential.
The best result I had was with VS / TNT2 Rx 17 in a ProStaff 95. The mains actually slid pretty well over the multi crosses. The only problem was that it was more pop/power than I'm used to. A higher tension might have worked but that increase friction between mains and crosses. Went back to gut/poly.
Other multi crosses that I tried failed to provide a low friction hybrid. In most cases the string bed got "stuck" out of position just like full-multi and full-gut.