With an open pattern 100'' you get into a territory of unpredictability, where you essentially want to close racquet's face more, lift the swing path a bit, and thus generate as much topspin as you can to regain the control and predictability from the topspin itself and by playing with bit higher net clearance to increase the margin of error. But it's a different playing style as well. Different tools for different masters.
I had my share of experience with 100'' 16x19 racquets (even with 16x18 100'') and it was enough for me, conclusion was that my playing style and grip don't get along that well with such, so I stay in 95-98'' territory. I'd be willing to try 100'' but only 16x20 or 18x20 interest me for my playing style.
Perhaps one day Paul decides to create an 18x20 TC100, now I'm willing to bet this racquet done by Paul's mastery and layup quality might be a particularly interesting tool. Because it might bridge the precision issues of open pattern 100'' racquets and marry them with some interesting features of 100'' racquets, such as bigger sweet spot, defensive forgiveness and increased stability.
@Racketdesign have you given a thought about bringing 18x20 TC100 to life ?