Defending champion: Bianca Andreescu (will not defend the title due to knee problems)
US Open winners from the past, who will participating in the 2020 edition: Serena Williams (1999, 2002, 2008, 2012-2014), Venus Williams (2000-2001), Kim Clijsters (2005, 2009-2010), Angelique Kerber (2016)...