@abmk
Ok, so you guys made me dig a little bit deeper on this topic, rather than just going off the top of my head, like I usually do.
2016 Murray vs 2006 Nadal at the
big tournaments only.
2016 Djoko played Murray 5 times (2 slams, 2 Masters, 1 WTF) = 3-2 Djoko.
2006 Fed played Nadal 5 times (2 slams, 2 Masters, 1 WTF) = 3-2 Nadal.
AO 2016 vs Wimby 2006 - Nadal was tougher as competition.
RG 2016 vs RG 2006 - Nadal was tougher as competition (duh!)
Rome 2016 vs Rome 2006 - Nadal of course (we are talking one of the best matches in history here).
Madrid 2016 vs MC 2006 - Nadal was tougher.
WTF 2016 vs WTF 2006 - Parity.
The level of play of the Top 10 in both years were fairly similar, give or take (Daveydenko, Nalby, A-Rod, Lube, Blake, Gonzo vs Wawa, Cilic, Raonic, Nishi, Thiem, Berdy), and it boiling down to Nadal/Murray, then I take it back. It's fairly obvious.
Verdict:
2006! Not to mention, the 2006 Fedal matches were much more competitive and entertaining to watch compared to the 2016 Djokoray ones.