If he is playing as good as people say he is then I think he has the advantage. He has full confidence in his game on this USO court likely under the roof. Since AO 21 he has pushed Djokovic to the limit in every match, nothing has been easy, it really feels like a Murray/Wawrinka style matchup where absolutely nothing comes easy for either guy in the match, every rally is a 20 shot grind, players very rarely make errors, every point is a battle.Med is indeed back to absolute peak. It is gonna be one hell of a fight. Medvedev is turbo charged and his confidence at an all time high, you could see it from his victory speech and interviews after beating Alcaraz.
Medvedev is a genuinely great hardcourter despite my dislike for him, I have respect for his game when in form. He has the younger legs and has definitely become battle tested. If his serve is back, watch out.
Only a fool would count out Djokovic from any match though and he will definitely not play as poorly as in 2021. Hope to watch a great match tomorrow.