In my opinion, there aren't any real negatives to the Wise. It's a very nice addition.
I suppose one could postulate some "negatives" to be...
1) Your machine needs to be somewhat near a power outlet.
2) Electricity is involved, so it's possible that a power surge/lightning could damage it.
3) A power outage could force you to resort to using your crank.
4) Like anything electronic, eventually something may need repair. After all, a well maintained lockout tensioner will likely last 30+ years, even with frequent use.
I could be wrong, but I doubt a Wise unit (even well taken care of) is going to be completely trouble free over a 30 year time period.
Note:
Since you're considering putting it onto your Neos 1000, just be aware that you will not have 360 degree rotation (which shouldn't be too big of a deal for you, since you're not accustomed to having 360 degree rotation anyway). Just keep in mind that you'll need to take extra caution, so that you don't swing the handle/grip of a mounted racquet right into the side of your diabolo/gripper assembly.
If your 2 center mains need to be pulled from the throat end (i.e. racquets that have 8 holes in the throat bridge) the handle/grip of your racquet is going to prevent those particular pulls from being straight and true.
Those particular strings are going to be forced a little to the side and those strings will also likely have to rub against the frame en route to the tensioner.
However, I'm pretty sure that some people have successfully added spacers/washers to the underside of their Neos 1000 turntable, which then raised it up enough that it solved the issue.
After doing the modification, they did have 360 degree rotation and the strings could then run, unfettered, to the tension head.