"CPPD develops when calcium pyrophosphate crystals build up in a joint. Crystals deposit first in the cartilage (the tissue that cushions inside joints) and can damage the cartilage. The crystals also can cause inflammation that leads to joint pain." I'm pushing 51 and just got my left knee drained of some fluid and then a cortisone shot injected into the joint. It feels much better. The thing is, I had it done last year on the other knee (although that one was much more swollen and more fluid was drained. Anyway, it's like gout, but a different crystallization process. Doesn't seem to respond to dietary changes. Any insights or comments? Thanks.