Decades ago, when the POG Mid (14x16) first came out, guys tried to play with SG or NG up to 15 Ga. SG & NG was not durable at all in that frame since they would break it within 2-4 hours. There weren't any 15 Ga multi back then, but they would not last very long either. Most went to Prince Pro Blend to try and get some string longevity. YMMV since it depends on your game. 3¢
The moderator,
@mikeler, plays with an ESP frame and he uses poly.