Yes, sure.
Remember how we use to say it was just impossible for anyone to win big titles with the big four around, because chance are you would have to beat two or even three of them to win a title?
Take a look at Berdych for example in 2010. He beats Federer, he beats Djokovic...now normally if you beat two such players it should mean a big title is in your hands, but he still had to play Nadal....
Next year, Tsonga GOATs against Federer coming back to win in five, but then has to face Djokovic 2011, and if he got past that, he had Nadal waiting in the final....
Del Potro 2013 plays an absolute epic with Djokovic in the semis, had he gotten through that, a fresh in form Murray would have finished him off easily in the final
Dimitrov playing the best season of his career and some of his best on grass at that point in 2014 dethrones Murray, only to run into Djokovic next round with Federer waiting in the final...
See a pattern? The non-big four players have to seriously GOAT like nothing before them, to get through such a gauntlet. It is bad enough trying to upset these guys in a best of three in a master, but try it in a best of five and you will see just how hard it is. And as grass is not a surface they play on as much, it makes the challenge that much more harder than on other surfaces.