Without question, weight and balance.
I can have a frame whose feel I love - but if its weight and balance are not what I'm comfortable with, the racquet will be useless to me - I wouldn't be able to hit my shots with it.
I can also have a racquet whose feel I hate - but if the weight and balance are right, I can play fine with it (although I still wouldn't like the feel, of course).
I think the vast majority of people feel the same way.
It's good to see that many people realize the importance of weight and balance.
Grip size is also quite important. In order to be able to hit your shots, it helps to have a grip size you're comfortable with.