I think you have to be a special kind of deluded to believe the result is going to change. The gulf between them was HUGE. Medvedev already showed end of last year, beginning of this, that nobody else is in his league on a hard court.
Yes, Berrettini and Zverev have both taken strides since then, but Medvedev is 25, not 34, he can play long matches and still be good to go, and neither of those guys has the game to beat him, and even if they did, they're still more likely to wet the bed when the going gets tough, just as they both have done so many times, just as they both did this past week (Well, Zverev did. Berrettini sort of just looked like he gave up) you can no more hit through Medvedev than you can Djokovic.
Nothing would have changed.
Actually, maybe Dan Evans would have gotten Novak like he did in Monte Carlo
The weight of history got to Djokovic all fortnight. The opposition was not going to change that. He hardly had some toweringly difficult first week, and he still made a meal of it.
There is minimal to suggest that his performance last night was due to physical exhaustion, far more that he was mentally tentative, and that his opponent was just too good/a match up that he hates. There is way more to indicate, based on their prior matchups, that what happened in Australia between them this year was the anomaly, and that the truth of this match up is always much more of a struggle.
Also, Botic gave Medvedev more trouble for those last two sets than Berrettini ever did to Novak.