Well,
Nothing plays like a fresh bed of syngut. So I have to put that out there.
That being the case, I'm starting to play this kind of setup myself (I'm a for-hire stringer type person, if you don't know me
).
I don't have any magic spells, but I will say this is a good idea. I hit quite flat, so I'm not a string breaker, but you'll get more life if you stick with a round poly.
That being said, I recently cut out a bed of Lynx Tour 1.25 mains / Velocity 1.30 noir crosses that was still playing pretty dang good. It'd been in rotation since late March so I didn't feel too bad cutting it out.
I replaced it with Iso-speed Grey Fire 1.25 & the new HEAD Syngut (white) 1.30. The stick is a Babolat VS Pure Strike (16x20 / 98in sq.), my tensions were 21.5/22.5 kg.
Oh, and I have a 5.0 customer who bought my Pure Strike 18x20 (2nd gen) frames, and after a series of trials, we've settled on TOURNA Grit 1.30 mains & Prince og Syngut 1.30 crosses and he likes it plenty.
That combo would also play well down a gauge (1.25/1.25) but I run the 16g stuff for him to buy him more lifespan; he's not super picky about feel, so for him the durability gains make for a worthwhile trade-off.
Good luck experimenting.
HTH
p.s. I agree with
@Humbi_HTX that the more elastic syngut helps buttress the poly and extend the lifespan. It also serves as a fuse, and when the syngut breaks (it will go first) the poly is almost certainly getting bagged out anyway, so you don't end up playing a dead af stringbed (to your detriment).