You do need to take extra precautions, one of the biggest is to avoid kinks in the string(I usually do a light manual prestretch of the gut to eliminate coil memory, it makes life easier and less chance of a kink). The prestretch, I clamp one end to machine (heavy machine) , and walk back to end, wrap the string around my hand and give it a pull back and you will feel the gut give in slightly, to help with the coil memory.With gut I normally string it as a 2 piece job, as there is less handeling of the string that way, but thats an individule preference.I always string the crosses top down as well even if the racquet you have allows bottom up,as the gut gets handled less on the top and thats where most of the hitting is. And the knots, be sure to hand pull only! Others here will tell you it is okay to pull with pliers or starting clamp, and that is fine but once every so often gut will get ruined by doing this as it can snap, and tying a good cinched up knot is possible using your fingers only, as there is no reason to over pull the knot as it will cinch up only so much, the rest puts extra stress on the string, I use the so called Parnell knot, as that cinches up nicely with your fingers.
The last couple cross strings you have to be very careful with as the string can unravel if it is overhandled, and if you do that, you will see it untwist, you would then need to retwist the string. This does not happen that much as it once did in the past, as todays guts have a coating to protect it so its less of an issue now,but can still happen so on the last couple crosses sometimes you need to pull the string all the way through each weave like you were sewing to keep the string from untwisting on the last cross string
You can also push or pull a loop on last 2 cross strings as less twisting of string that way.
Just be careful and you will be okay, just don't be rough with it , take your time and it will go well with no problems.If you rush, and pull hard when it kinks, and you can ruin an expensive piece of string, so take your time and go for it.
Oh, one more thing, if your machine has a diablo(nosecone), its best to use it, as it puts less stress on the string, as the tension jaws don't have to apply as much tension to hold the string, and the string will enter the tension clamp at the same angle. Also, if you have to pull a string twice for any reason, I will then wrap the gut two times around the diablo the second time as that way the tension clamp will be at a different spot on the string, so less wear is placed in one spot.
