Nope. But there's no way you are facing an ATP serve with a 250 g racquet. On the other end of a spectrum, a racquet too heavy is just gonna be cumbersome and not make sense. 400 g is probably the upper end, and even that seems like an overkill in today's modern game.
There were reports of Murray using a 400 g racquet earlier on in his career, although he now hovers around 360 g.